Mepilex® Up is a thin, highly conformable soft silicone dressing made to handle high volumes of exudate and reduce the risk of leakage, even under compression.
Exudate is where leg ulcer care comes undone
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Chronic wounds produce exudate that is unpredictable in both volume and viscosity. When a dressing can't keep up, fluid can pool until it overwhelms the dressing, tracking onto intact skin and leaking through to clothing, bedding, and compression bandaging.
The cost isn't only clinical. Patient quality of life is significantly affected by living with chronic exudate: the leakage, the odor, the unscheduled dressing changes and the loss of confidence that comes with them.1,2,3
But now things are looking up.
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Meet Mepilex® Up, the thin dressing built to minimize leakage
Mepilex® Up is the thin dressing with the patented dimpled foam design, made to handle high volumes of exudate and reduce the risk of leakage, even under compression.4 Its low profile conforms to difficult-to-dress areas and sits comfortably under compression bandaging, while the dimpled foam spreads fluid evenly in all directions, even against gravity, keeping it moving away from the wound and the surrounding skin.4-5
- Absorbs both low and high viscous exudate
- Higher fluid handling capacity than other foam dressings6
- Minimizes risk of leakage, even under compression4
How it Works
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The soft silicone Safetac® layer seals the wound margins, channeling exudate vertically into the foam and helping prevent maceration.
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A patented dimpled foam
The patented foam structure creates a proprietary dimpled surface pattern.
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Fluid spreads in all directions
The dimpled pattern enables the dressing to spread fluids evenly in all directions, even against gravity.
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Managed, without leaking
The innovative and unique spreading properties minimizes the risk of leakage and may contribute to long wear time and fewer dressing changes.
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Thin enough to sit under compression
With its low profile, Mepilex® Up is designed to conform well to difficult to dress areas.7 It can be cut to shape, lifted and adjusted without loss of adherent properties, and used under compression bandaging.
Mepilex® Up conforms better than other foam dressings.6
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Handles high volumes, thin and viscous alike
Mepilex® Up manages exudate corresponding to low to highly exudating wounds, with and without compression therapy, and absorbs high viscous fluid under compression bandages.
Despite its thinness, Mepilex® Up can handle fluids better than other foam dressings.6
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Protects the skin around the wound
Mepilex® Up minimizes the risk for maceration.8 The Safetac® layer does not adhere to the moist wound bed but adheres gently to dry skin, minimizing trauma to the wound bed and surrounding skin, and minimizing pain to the patient during dressing removal.9
The evidence: How Mepilex® Up performed in chronic wounds
In a clinical investigation using Mepilex® Up as part of a treatment regimen, 68 patients with moderately and largely exuding chronic wounds – 34 venous leg ulcers and 34 diabetic foot ulcers – were followed for up to 6 weeks.¹⁰
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0of assessments judged wounds improved or healed
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0Median wound area reduction at final visit
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0Average wear time
Inside the dressing
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Every layer of Mepilex® Up does a job – here's what each one contributes.
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1 - Low profile polyurethane foam pad
Manages high fluid volumes over a long wear time; highly conformable.4
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2 - Dimpled surface pattern
Spreads exudate in all directions, even under compression and against gravity.4,5
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3 - Polyurethane backing film
Breathable and water resistant; secures fluid and evaporates excess moistures.
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4 - Safetac® layer
Adheres to dry skin but not the wound bed; seals wound margins and reduces the risk of maceration; reduces pain at dressing changes.8,9
In venous leg ulcer care, every step counts.
Clean. Cover. Compress. Mepilex® Up handles the cover. See the full protocol and the evidence behind each step.
See the Full ProtocolSee Mepilex® Up in action
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Watch how fluid moves through the dressing, and hear from patients and clinicians who use it.
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How exudate moves through Mepilex® Up
A time-lapse view of fluid spreading through the dimpled foam structure.
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A patient and clinician perspective
A first-hand account of living with a highly exuding venous leg ulcer, and what changed.
More than products. A partner at every step.
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Better wound care takes more than what's in the box. Mölnlycke backs every product with the evidence, education, and support clinicians need to deliver connected care with confidence.
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Innovative Products
Purpose-built products designed for the real challenges of wound care, backed by evidence clinicians can trust.
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Clinical Education
Practical training, tools, and resources that build clinician confidence, from onboarding a new protocol to everyday practice.
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Patient Resources
Clear, easy-to-understand materials that help patients follow their care plan and stay engaged in their own healing.
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Detailed Support
Knowledgeable reps and clinical resources that help teams put best practices into place and keep them there.
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Ordering Information
Product Code Size In (cm) Pcs/box Pcs/case HCPCS 212199 4"x4" (10x10 cm) 10 40 A6209 212299
4"x8" (10x20 cm) 10 30 A6210 212399 6"x6" (15x15 cm) 10 30 A6210 212499 8"x8" (20x20 cm) 10 30 A6211 -
References
- Green J, Jester R, McKinley R, Pooler Patient perspectives of their leg ulcer journey. J Wound Care. 2013 Feb; 22(2):58, 60-2, 64-6. doi: 10.12968/jowc.2013.22.2.58. PMID: 23665659
- Phillips, P, Lumley, E, Duncan, R, et A systematic review of qualitative research into people’s experiences of living with venous leg ulcers. J Adv Nurs. 2018; 74: 550–563. https://doi.org/ 10.1111/jan.13465
- Kelechi, T.J., Muise-Helmericks, R.C., Theeke, L.A. et al. An observational study protocol to explore loneliness and systemic inflammation in an older adult population with chronic venous leg ulcers. BMC Geriatr 21, 118 (2021). https://doi.org/10.1186/s12877-021-02060-w
- Mölnlycke Health Care. Test report PD-701547. Data on file.
- Mölnlycke Health Care. Test report PD-701546.
- Mölnlycke Health Care. Test Report PD-741994. Data on file 2024.
- Mölnlycke Health Care Data on file 2024.
- Wiberg A.B. et al. Preventing maceration with a soft silicone dressing: in-vitro evaluations. Poster presented at the 3rd Congress of the WUWHS, Toronto, Canada, 2008.
- Gee Kee E.L. et al. Randomized controlled trial of three burns dressings for partial thickness burns in children. Burns, 2014.
- Mölnlycke Health Care. Data on file. 2024.